Cholinergic modulation of spatial learning, memory and navigation
نویسندگان
چکیده
منابع مشابه
prelimbic of medial prefrontal cortex GABA modulation through testosterone on spatial learning and memory
Prefrontal cortex (PFC) is involved in multiple functions including attentional , spatial orientation, short and long-term memory. Our previous study indicated that microinjection of testosterone in CA1 impaired spatial learning and memory. Some evidence suggests that impairment effect of testosterone is mediated by GABAergic system. In the present study, we investigated the interaction of test...
متن کاملprelimbic of medial prefrontal cortex GABA modulation through testosterone on spatial learning and memory
Prefrontal cortex (PFC) is involved in multiple functions including attentional , spatial orientation, short and long-term memory. Our previous study indicated that microinjection of testosterone in CA1 impaired spatial learning and memory. Some evidence suggests that impairment effect of testosterone is mediated by GABAergic system. In the present study, we investigated the interaction of test...
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Suppression of cholinergic receptors and inactivation of the septum impair short-term memory, and disrupt place cell and grid cell activity in the medial temporal lobe (MTL). Location-dependent hippocampal place cell firing during active waking, when the acetylcholine level is high, switches to time-compressed replay activity during quiet waking and slow-wave-sleep (SWS), when the acetylcholine...
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ژورنال
عنوان ژورنال: European Journal of Neuroscience
سال: 2018
ISSN: 0953-816X
DOI: 10.1111/ejn.14089